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KMID : 0359919880070010182
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Korean Journal of Nephrology
1988 Volume.7 No. 1 p.182 ~ p.185
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Rifampin Induced Acute Renal Failure
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Abstract
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administration. During that time she was hospitalized at a local hospital and anti-tuberculous medication was discontinued for 4 months. Again she took a single dose of rifampin (450mg) and fever, chill, itching, nausea, vomiting, abdominal pain and reddish mucoid stool developed. Oliguria also occurred and abdominal pain became severe. She was referred to Yeungnam University Medical Center and was treated with 8 times of hemodialysis. Oliguric phases lasted about 11 days and she recovered slowly but without any sequelae. On 9th hospital day we prescribed isoniazid, ethambutol and cycloserine and no side-effect was noted. There was no evidence of hemolysis and we presume a hypersensitivity reaction was operating in this case. The authors report a case of rifampin-induced acute renal failure with review of literature.
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